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Apoptosis induced by infection with Gilchrist strain of rubella virus.(Brief Article)

Vaccine Weekly

| February 05, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 FEB 5 - (NewsRx.com & NewsRx.net) -- According to recent research from Argentina, "Apoptosis is an active process of cellular self-destruction, which can be initiated in response to several stimuli such as toxic substances, hormones, cytokines, trophic or osmotic modifications and viral infections. In this study, we demonstrate that in vitro rubella-virus (RV) induced cell death exhibited properties of apoptosis, characterized by condensation and segmentation of nuclei and internucleosomal cleavage of nuclear DNA."

"Apoptosis was not seen in the cells absorbed with UV-inactivated virus, indicating that the viral replication is required for the induction of apoptosis," said Lidia Dora Martinez and colleagues at Universidad Nacional de Cordoba. "Our results suggest that most of the cells ...

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Source: HighBeam Research, Apoptosis induced by infection with Gilchrist strain of rubella...

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