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Active Chlamydia trachomatis infection correlated to spontaneous abortion.

Women's Health Weekly

| February 06, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 FEB 6 - (NewsRx.com & NewsRx.net) -- Couples infected with Chlamydia trachomatis stand a higher risk for early pregnancy lost.

According to a study from Chile, "the incidence of Chlamydia trachomatis (Ct) infection and the possible correlation between couples presenting with first-trimester spontaneous abortions and active Ct infection was assessed. Additionally, the ability of Ct to infect zona-free hamster oocytes was explored by incubating the oocytes with spermatozoa from infected patients. A total of 961 women and 750 men consulting our reproductive medicine centre were screened for Ct using direct immunofluorescence."

"The general incidence of Ct infection was 9.4% in females ( 90 of 961) and 13.9% in males ( 104 of 750). In women with spontaneous abortions the incidence of Ct was 21.0% ( 14 of 66) compared with 8.9% ( 23 of 59) for women without spontaneous abortions and term pregnancies (Chi-square, p

"When both partners of the couples were considered (one or both partners infected), the incidence rose to 68.8% (22 of 32) (Chi-square, p

"In vitro studies using electron microscopy demonstrated the presence of Ct on the surface of and inside the oocyte. These results indicate a correlation between an active Ct infection and ...

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