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Bone morphogenetic protein-15 may be fertility regulator.
2003 FEB 6 - (NewsRx.com & NewsRx.net) -- Scientists report bone morphogenetic protein-15 regulates only one of a few hormones associated with human reproduction and may thus be a fertility modulator.
According to a study from the United States, "bone morphogenetic protein-15 (BMP-15) has been known to be an oocyte-specific factor and regulate granulosa cell functions. Here, we report that BMP-15 is also expressed in the well established gonadotrope cell line, LbetaT2 and mouse pituitary tissue,"
"Interestingly, BMP-15 stimulates FSH-beta subunit transcription in LbetaT2 cells without affecting LH-beta and GnRH receptor transcription," stated F. Otsuka and coauthors, University of California San Diego, School of Medicine.
"These findings, therefore, suggest a possible autocrine control mechanism selective for FSH-beta synthesis by BMP-15. Moreover, BMP-15 exerts a potent and selective stimulation of FSH, but not LH, secretion by primary pituitary cells."
"Taken together, we hypothesize that BMP-15 could play a physiological role in the monotropic rise ...
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- Press release article from: PR Newswire October 17, 2001 700+ words
...Humanitarian Device Exemption (HDE) status for OP-1 Implant (Osteogenic Protein 1). The clearance marks the first for a BMP in the United States. Osteogenic Protein 1 is Stryker's patented recombinant protein, which induces bone formation. The...
- Research on bone morphogenetic protein reported by B.S. Miguel et al.
- Newspaper article from: Blood Weekly December 3, 2009 700+ words
...in combination with bone morphogenetic protein (BMP)-2, because NMP...5,8 induced by BMP-2," wrote B...colleagues (see also Bone Morphogenetic Protein). The researchers...chemical NMP enhances BMP activity by increasing...
- Studies in the area of bone morphogenetic protein reported from Osaka Dental...
- Newspaper article from: Blood Weekly December 10, 2009 700+ words
...report (see also Bone Morphogenetic Protein). "In...controlled release of bone morphogenetic protein 2 (BMP-2) for alveolar...hydrogels incorporating BMP-2 is a promising...controlled release of bone morphogenetic protein: an experimental...
- New findings in bone morphogenetic protein described from Medical...
- Newspaper article from: Blood Weekly December 3, 2009 700+ words
...containing bone morphogenetic protein 2 (BMP-2) combined...see also Bone Morphogenetic Protein...collagen and BMP-2/PLGA...quantity of BMP-2 and autologous...Transplanted Bone Morphogenetic Protein/Poly...
- Research reports on bone morphogenetic protein from Stanford University provide...
- Newspaper article from: Biotech Week November 18, 2009 700+ words
...loss of function of bone morphogenetic protein (BMP) receptor (BMPR...to S100A4/Mts1 or BMP-2. Reduced CLIC4...a single ligand (BMP-2 or S100A4/Mts1...University (see also Bone Morphogenetic Protein). The researchers...
- Studies from Z. Dahabreh et al have provided new data on bone morphogenetic...
- Newspaper article from: Biotech Week November 18, 2009 700+ words
...graft (ICBG) or bone morphogenetic protein-7 (BMP-7), is presented...actual price of the BMP-7," wrote Z...colleagues (see also Bone Morphogenetic Protein). The researchers...efficacy and safety of BMP-7 in comparison...
- Bone morphogenetic protein accelerates healing of long-bone critical defects.
- Newspaper article from: Drug Week February 20, 2004 700+ words
...cancellous bone and bone morphogenetic protein (BMP)-7 or bone marrow...including 300 microgram bone morphogenetic protein (BMP)-7 and in six animals...cancellous bone and bone morphogenetic protein (BMP)-7 or bone marrow...
- University of Halle-Wittenberg publishes research in bone morphogenetic protein.
- Newspaper article from: Biotech Week December 2, 2009 700+ words
...the pro-form of bone morphogenetic protein-2 (BMP-2), a member of...also differed from BMP-2 in its capacity...Wittenberg (see also Bone Morphogenetic Protein). The researchers...the pro-domain of BMP-2 can alter the...
Source: HighBeam Research, Bone morphogenetic protein-15 may be fertility regulator.