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Insecticide affects male offspring of pregnant and lactating rats.

Women's Health Weekly

| February 06, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 FEB 6 - (NewsRx.com & NewsRx.net) -- The insectide deltamethrin appears to cause subtle changes in male rats that are exposed to it while in utero or while suckling.

According to a study from Brazil, "the effects of low doses of deltamethrin administered to female rats on the reproductive system of male offspring were examined."

"The dams (n=10-12/group) were treated daily by oral gavage with 0, 1.0, 2.0, and 4.0 mg deltamethrin/kg from day 1 of pregnancy to day 21 of lactation. Maternal and reproductive outcome data and male sexual development landmarks were assessed. Fertility, sexual behavior, and a large number of reproductive endpoints, such as organ weights, sperm evaluations, testosterone concentration, and testicular histology were examined on adult male offspring," stated A.J.M. Andrade and coauthors, Federal University of Parana, Department of Pharmacology.

"No signs of maternal toxicity were detected at the dose levels tested. Significantly adverse effects were only seen on testicular and epididymal absolute weights and the diameter of seminiferous tubules in the group treated with the highest dose of deltamethrin (4.0 mg/kg)."

"The results indicate ...

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Source: HighBeam Research, Insecticide affects male offspring of pregnant and lactating rats.

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