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Derivatives from food packaging don't show estrogenic activity.
2003 FEB 6 - (NewsRx.com & NewsRx.net) -- Chemicals derived from coatings used for packing food don't demonstrate estrogenic activity when administered to human breast cancer cells.
"Bisphenol A diglycidyl ether (BADGE) is an epoxy resin monomer. Epoxy-based solution coatings are used in many applications as additives for a variety of plastic coatings in food packaging. It is well known that unreacted BADGE can migrate from epoxy-based packing materials into foods," researchers in Japan reported.
"Not only BADGE but also its derivatives can easily migrate into foods and it is likely that we intake BADGE and its derivatives through food or drink. Recently, endocrine disrupting chemicals (EDCs) have attracted attention because they have been shown to affect reproduction in wildlife," remarked H. Nakazawa and colleagues, Hoshi University.
"The estrogenic activity of BADGE derivatives has not previously been investigated. Therefore, we investigated the estrogenic activity of the BADGE derivatives, dihydrolysed BADGE (BADGE-4OH) and chlorohydroxy BADGE (BADGE-2Cl), using breast cancer cell (T47D) proliferation assay and estrogen receptor ...
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Source: HighBeam Research, Derivatives from food packaging don't show estrogenic activity.