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2003 FEB 6 - (NewsRx.com & NewsRx.net) -- Pregnant women diagnosed with an abnormal condition of pregnancy called pre-eclampsia, which raises blood pressure, demonstrated significantly smaller upper airways than did either nonpregnant women or those with normal pregnancies, according to a new study.
The results could explain why such patients have increased upper airway resistance while sleeping and a resulting rise in blood pressure.
Writing in the second issue for January 2003 of the American Journal of Respiratory and Critical Care Medicine, Neil J. Douglas, MD, of the Edinburgh Sleep Centre and department of reproductive and developmental sciences, University of Edinburgh, along with seven associates, measured upper airway caliber in 137 women. They checked 50 women in the third trimester of a normal pregnancy, 37 women with pre-eclampsia, and 50 healthy, nonpregnant women.
Using an acoustic reflection technique, the researchers measured the dimensions of the women's airway in a seated position, lying on their back, and lying on their left side.
According to the authors, the patients with pre-eclampsia had significantly narrower upper airways when seated and when supine than did nonpregnant women.
Pre-eclampsia, which develops in 5% of pregnancies, does not occur until the 20th week of gestation or later. It is characterized by hypertension, edema in the face and hands, and the presence of protein in the urine. Additional problems for these patients ...