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2003 JAN 9 - (NewsRx.com & NewsRx.net) -- A Mayo Clinic study of more than 41,000 postmenopausal women in Iowa provides new evidence that the most common type of lung cancer in women is more closely linked to smoking cigarettes than previously recognized.
Lung cancer has been the leading cause of cancer death in women for more than a decade. In 2000, about 68,000 American women died of lung cancer. That's compared to about 40,000 women who died from breast cancer.
While the lung cancer-tobacco connection is well-established, researchers have suspected that adenocarcinoma - which accounts for over 40% of lung cancer in women - was linked to other, unknown risk factors. That's because adenocarcinoma, more so than other forms of lung cancer, strikes women who have never smoked.
The Mayo Clinic study, published in the December 15, 2002, issue of the American Journal of Epidemiology, used a statistical model to compare the incidence rates of the three types of lung cancer: adenocarcinoma, squamous cell carcinoma and small cell carcinoma.
"We found adenocarcinoma of the lung is more strongly associated with smoking than previously recognized," said Ping Yang, MD, PhD, a Mayo Clinic epidemiologist and lead researcher on the study.
For example, among 10,000 women who do not smoke, each year 3 women will develop any lung cancer, 2 of them being adenocarcinoma. Among the same number of women who smoked a pack of cigarettes a day for 20-39 years, 30 will develop lung cancer each year: 14 adenocarcinoma, 8 squamous cell and 8 small cell lung cancer. All three types of lung cancer are very serious illnesses.
"Knowing the very strong association between smoking and adenocarinoma is important because researchers ...
Source: HighBeam Research, New evidence links smoking and lung cancer in women.