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Hormone therapy technology licensed From Wake Forest.(BioSante Pharmaceuticals Inc. signs licensing agreement for triple hormone therapy technology)

Women's Health Weekly

| January 09, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 JAN 9 - (NewsRx.com & NewsRx.net) -- BioSante Pharmaceuticals, Inc., (BISP) announced it has licensed three patents encompassing new combinations of hormone therapies, known as triple hormone therapy, by any route of administration, from Wake Forest University School of Medicine.

Also included in the license is an option to use triple hormones in contraceptives.

The Wake Forest patents cover novel combinations of estrogens and progestins with androgens, such as testosterone, which may have beneficial effects in women. Currently, estrogen plus progestin is indicated for the treatment of menopausal symptoms, including hot flashes and vaginal atrophy, for women with an intact uterus. Testosterone is thought to further alleviate symptoms of menopause and female sexual dysfunction in postmenopausal women.

"This license agreement with Wake Forest for new combination hormone therapies is a very valuable addition to BioSante's hormone therapy product pipeline in development," said Stephen M. Simes, president and chief executive officer of BioSante. "Our products are topical gel formulations for men and women. These gels provide continuous systemic levels of the hormones, which may result in less potential for side effects. With more attention being focused on the safety and efficacy of hormone therapy products, especially among women and their healthcare providers, we believe BioSante's portfolio of hormone therapy gel products positions us well to gain acceptance and market share in the treatment of menopausal symptoms, among other indications."

BioSante currently is testing Bio-T-Gel (gel formulations of testosterone for men), Bio-E-Gel (estradiol for women), and LibiGel (testosterone for treatment of ...

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