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No link found between MMR vaccine and autism.
2003 JAN 8 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A large Danish study detected no increase in the risk of developing autism in children who received the measles-mumps-rubella (MMR) vaccine, according to a report in the New England Journal of Medicine.
Recent controversy over the safety of the MMR vaccine has focused on the possibility of an increased incidence of autism among children who receive the vaccination.
Kreesten Meldgaard Madsen and colleagues at the Danish Epidemiology Science Center in Denmark and the U.S. National Center on Birth Defects and Developmental Disabilities conducted a retrospective study on the association between MMR immunization and autism involving 537,303 children born in Denmark from January 1991 through December 1998.
This cohort of children represented 2,129,864 person-years (A population-based study of measles, mumps, and rubella vaccination and autism. N Engl J Med, 2002;347(19):1477-1482).
The investigators found that 82% of the children (440,655) had been immunized with the MMR vaccine. Total number of autism cases was 316, with another 422 children diagnosed with disorders related to autism.
Relative risk of autism in the immunized children versus the unimmunized children, was 0.92 (95% confidence interval, 0.68-1.24), after adjusting for potential confounding factors. The corresponding ...
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