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Erosive vulvar lichen planus may contribute to intrapartner spread of HCV.(hepatitis C virus)
2003 JAN 2 - (NewsRx.com & NewsRx.net) -- Lichen planus affecting genitalia may cause hepatitis C virus (HCV) infection between sexual partners, researchers suggest.
"Lichen planus (LP), common mucocutaneous disorder, involves not only oral mucosa and skin but genitalia membrane. LP is frequently seen in patients with HCV infection. This study evaluated patients with HCV-associated oral lichen planus (OLP) for vulvar and vaginal LP involvement, and the possible intraspousal transmission of HCV," wrote researchers in Japan.
"We examined a total of 24 female Japanese patients with OLP for genitalia LP: 14 OLP-HCV positive and 10 OLP-HCV negative. All subjects were evaluated for genital LP by a gynecologist. All 24 subjects and 10 of the husbands were tested for anti-HCV and serum HCV RNA," wrote Y. Nagao and colleagues, Kurume University.
"Vulvar LP was observed in 10 (41.7%) of 24 patients with OLP. Vulvar LP in 14 (OLP-HCV positive) and 10 patients (OLP-HCV negative) [was] observed in 42.9% and 40%, respectively," the authors said.
They found "no significant differences (age, sites of OLP, blood transfusion, HCV infection, and degree of liver diseases) between the vulvar LP and non-vulvar LP patients."
"Two spouses of 10 married couples were shown to be infected with HCV. In one couple with HCV ...
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Source: HighBeam Research, Erosive vulvar lichen planus may contribute to intrapartner spread of...