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Obesity link identified.(leptin found to promote breast cancer cell growth)
2002 DEC 26 - (NewsRx.com & NewsRx.net) -- Leptin, the growth factor associated with weight gain, has been found to promote breast cancer cell growth, according to a new study.
The research also found a lack of leptin or its receptor is associated with a lack of breast tissue development in mice. Previous research identified an association between obesity and breast cancer, but scientists were unsure of what was responsible for linking these two diseases. New research, led by University of Minnesota researcher Margot Cleary, PhD, may close that gap in understanding.
"These findings may explain why weight gain, which is accompanied by higher-than-expected leptin concentrations, also has been associated with increased breast cancer risk," said Cleary. "Preventive measures need to be taken to control these deadly diseases." The findingers were published in the November 20, 2002, issue of the Journal of the National Cancer Institute.
Obesity is considered a risk factor for breast cancer, and women who are obese tend, at the time of diagnosis, to have more aggressive disease with a poorer prognosis. Increased leptin levels have been tied to increased body fat levels and obesity. Research ...
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Source: HighBeam Research, Obesity link identified.(leptin found to promote breast cancer cell...