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Aspirin inhibits tumor growth, USF lab study finds.(University of South Florida)(Brief Article)

Women's Health Weekly

| December 19, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 DEC 19 - (NewsRx.com & NewsRx.net) -- Aspirin may reduce ovarian cancer growth, a new study has shown.

The study, published in Obstetrics and Gynecology, demonstrated that aspirin inhibited ovarian tumor cell growth by as much as 68%. The higher the dosage of aspirin added to the culture of ovarian cancer cells, the more growth inhibition was observed.

The researchers also found that combining aspirin with a monoclonal antibody specific for the HER-2/neu protein created even greater suppression of growth than treating the tumor cells with aspirin alone. This combination decreased ovarian cancer cell growth by 84%.

HER-2/neu is a receptor protein on the tumor cell surface that binds to a substance that stimulates growth. The protein is elevated in a third of ovarian cancers.

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