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2002 DEC 19 - (NewsRx.com & NewsRx.net) -- A family history of breast cancer does not increase a woman's chances of developing womb cancer, finds a 20-year study in the Journal of Medical Genetics.
Cancers of the lining of the womb (endometrium) and breast share some of the same reproductive, hormonal, and lifestyle risk factors. The evidence for a genetic link between the two types of cancer has so far been inconclusive.
But a team from the U.S. National Cancer Institute and the Uniformed Services University of the Health Sciences in Bethesda, Maryland, investigated whether women who had a family history of breast cancer were more likely to develop endometrial cancer than women with no such family history. They studied this in more than 37,500 former participants of a U.S. national breast screening program (the Breast Cancer Detection Demonstration Project).
The women were monitored for an average of almost 14 years during the study, which started in 1979 and completed in 1998. Their average age was 55 at the start of monitoring. Information was also collected on any cases of breast cancer among their first- and second-degree female relatives.
During the study, endometrial cancer was diagnosed in 648 women. There was no evidence that breast cancer in either a first- or ...
Source: HighBeam Research, Family history of breast cancer does not increase risk.