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We all know that it's important to keep cholesterol under control. But the dirty little secret of cardiology is that more than half the people who suffer heart attacks have normal cholesterol levels. So how do you know if you're at risk? A simple test may help, according to a major study published recently in The New England Journal of Medicine.
Harvard cardiologist Paul Ridker, director of the Center for Cardiovascular Disease Prevention at Brigham and Women's Hospital, tested nearly 28,000 women for both LDL ("bad") cholesterol and blood levels of a substance called C-reactive protein, or CRP, an indicator of arterial inflammation. After eight years, he tallied up heart attacks and strokes among the women. Adjusting for risk factors like smoking and diabetes, he found that high cholesterol increased the women's heart-attack risk up to ...