AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Rabbit oral papillomavirus appears best choice for developing HPV vaccine.(human papillomavirus)
2002 DEC 11 - (NewsRx.com & NewsRx.net) -- A comparison of animal papillomaviruses to the human variety suggests rabbit oral papillomavirus is best suited for study of the "life cycles of mucosal papillomavirus types and for the development of prophylactic vaccines."
"Animal papillomaviruses are widely used as models to study papillomavirus infection in humans despite differences in genome organization and tissue tropism," noted W.L. Peh and colleagues, National Institute Medical Research, Ridgeway, UK.
Peh's team compared the life cycles of 10 types of papillomavirus to see which most resembled human papillomavirus (HPV) disease.
"Three phases in the life cycles of all viruses were apparent using antibodies that distinguish between early events, the onset of viral genome amplification, and the expression of capsid proteins," the researchers said. "The initiation of these phases follows a highly ordered pattern that appears important for the production of virus particles."
They reported that each type of virus - including canine oral papillomavirus, rabbit oral papillomavirus (ROPV), cottontail rabbit papillomavirus (CRPV), bovine papillomavirus type 1, and human papillomavirus types 1, 2, 11, and 16 - "showed a distinctive gene expression pattern that could be explained in part by differences in tissue tropism, transmission route, and persistence."
"As the timing of life cycle events affects the accessibility of viral ...
- Rabbit oral papillomavirus appears best choice for developing HPV...
- Newspaper article from: Virus Weekly December 10, 2002 700+ words
...which most resembled human papillomavirus (HPV) disease...virus - including canine oral papillomavirus, rabbit oral papillomavirus (ROPV), cottontail...papillomavirus type 1, and human papillomavirus types 1, 2, 11, and...
- Rabbit oral papillomavirus appears best choice for developing HPV vaccine.
- Magazine article from: Women's Health Weekly December 12, 2002 700+ words
...which most resembled human papillomavirus (HPV) disease...virus - including canine oral papillomavirus, rabbit oral papillomavirus (ROPV), cottontail...papillomavirus type 1, and human papillomavirus types 1, 2, 11, and...
- Human papillomavirus infection: pathogenesis suggests new strategies for...
- Magazine article from: British Medical Journal Hines, Jeffrey F. Ghim, Shin-Je Jenson, A. Bennett March 2, 1996 700+ words
...associated with human papillomavirus often exhibit...mucosotropic anogenital human papillomavirus types have in...particles of canine oral papillomavirus are completely...like particles of human papillomavirus are candidates...
- New human papillomavirus research from K. Brandes et al outlined.
- Magazine article from: Women's Health Weekly February 19, 2009 700+ words
...fragments of canine Oral papillomavirus (COPV) DNA were...colleagues (see also Human Papillomavirus). The researchers...Detection of Canine Oral Papillomavirus DNA in Conjunctival...Histopathology, Human Papillomavirus, Hyperplasia...
- MEDIMMUNE IN-LICENSES KEY HUMAN PAPILLOMAVIRUS VACCINE INTELLECTUAL PROPERTY...
- Press release article from: PR Newswire June 26, 1996 700+ words
...applications in the field of human papillomavirus (HPV) vaccines. The licensing...and cervical cancer. "Human papillomavirus is both an important medical...with a virus called canine oral papillomavirus (COPV), which mimics...
- MEDIMMUNE ACQUIRES EXCLUSIVE LICENSE TO HUMAN PAPILLOMAVIRUS VACCINE TECHNOLOGY...
- Press release article from: PR Newswire October 5, 1995 700+ words
...MedImmune has licensed exclusive worldwide rights to human papillomavirus (HPV) vaccine technology developed at University of...analogous model in dogs with a virus called canine oral papillomavirus (COPV). COPV mimics HPV infection more closely than...
- MedImmune Files IND To Begin Human Clinical Trials For First Preventative Human...
- Press release article from: PR Newswire December 11, 1996 700+ words
...clinical trials with a vaccine for the prevention of human papillomavirus (HPV) disease of the genital tract. The clinical trial...infection. The model involves a virus called canine oral papillomavirus (COPV) which mimics HPV infection closely because it...
- Is human papillomavirus an infectious cause of non-cervical anogenital tract...
- Magazine article from: British Medical Journal Strickler, Howard D. Schiffman, Mark H. September 13, 1997 700+ words
...demonstrate in the study of human papillomavirus infection as a cause of...In cervical cancers human papillomavirus DNA can be detected in...Moreover, cervical human papillomavirus has been detected before...
- Cigarette smoking and human papillomavirus in patients with reported cervical...
- Magazine article from: British Medical Journal Burger, M.P.M. Hollema, H. Gouw, A.S.H. Pieters, W.J.L.M. Quint, W.G.V. March 20, 1993 700+ words
...smoking and infection with oncogenic human papillomavirus. It has been suggested that smoking...the infection and persistence of human papillomavirus. Design--Cross sectional epidemiological...analysis of cervical scrapes for human papillomavirus, and morphological examination...
- Predictive value of human papillomavirus type for histological diagnosis of...
- Magazine article from: British Medical Journal Burger, M.P.M. Hollema, H. Pieters, W.J.L.M. Quint, W.G.V. January 14, 1995 700+ words
...The broad spectrum of different human papillomavirus types has recently been grouped...tree lead to specific groups of human papillomavirus types with similar tissue tropism...viruses such as types 31 and 33. Human papillomavirus type 18 belongs to a separate main...
Source: HighBeam Research, Rabbit oral papillomavirus appears best choice for developing HPV...