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Leukapheresis products are potential sources of quantities of dendritic cells.
2002 DEC 11 - (NewsRx.com & NewsRx.net) -- Researchers in Australia have suggested what may be a practical way to obtain cells for studies of dendritic cell-based vaccines.
F.J. Radcliff and colleagues, Royal Children's Hospital, described their study methods: "The number of dendritic cells (DC) circulating in the peripheral blood of cancer patients were monitored at multiple time points during chemotherapy and granulocyte colony-stimulating factor (G-CSF) support. DC were identified via the lack of expression of standard lineage markers and high expression of HLA-DR (LN-/DR+). The expression of DC-associated markers, including CD83, CD11c, IL-3Ra (CDw123) and CD86, within this LN-/DR+ population was also monitored."
The researchers reported that "[m]aximal mobilization occurred during recovery on day 12, with a mean 32-fold increase in LN-/DR+ numbers. The most striking increase was observed in the LN-/DR+/CD83+ cell population: 12 days after commencement of treatment, the proportion of these cells had increased by approximately 120-fold when compared with baseline. Peripheral blood mononuclear cell (PBMC) and CD34+ cell numbers also peaked 12 days into the ...
- Dendritic cells fused with leukemia blast cells activate lymphocytes.
- Newspaper article from: Clinical Oncology Week October 11, 2004 700+ words
...amp; NewsRx.net) -- Dendritic cells fused with core-binding...published their study in the British Journal of Haematology (Dendritic cells fused with core-binding...contact information for the British Journal of Haematology is: Blackwell...
- Dendritic cells induce antitumor CD8 cells in chronic lymphocytic leukemia.
- Newspaper article from: Cancer Vaccine Week March 24, 2003 700+ words
...with idiotype-pulsed dendritic cells in vitro," said Francoise...their study in the British Journal of Haematology (Idiotype-pulsed dendritic cells are able to induce...To subscribe to the British Journal of Haematology, contact...
- Leukapheresis products are potential sources of quantities of dendritic cells.
- Newspaper article from: Cancer Weekly December 10, 2002 700+ words
...methods: "The number of dendritic cells (DC) circulating in...was published in the British Journal of Haematology (Mobilization of dendritic cells in cancer patients treated...To subscribe to the British Journal of Haematology, contact...
- Dendritic Cells Have Immunotherapeutic Potential in Myeloma Treatment.
- Newspaper article from: Immunotherapy Weekly June 29, 1998 700+ words
Dendritic cells generated from mononuclear...United Kingdom ("Dendritic Cells Cultured from Mononuclear...Human Herpesvirus 8," British Journal of Haematology, 1998;100:793-796). Dendritic cells (DC) are antigen...
- Human Herpesvirus 8 Dendritic Cells Have Immunotherapeutic Potential in Myeloma...
- Newspaper article from: Blood Weekly June 29, 1998 700+ words
Dendritic cells generated from mononuclear...United Kingdom ("Dendritic Cells Cultured from Mononuclear...Human Herpesvirus 8," British Journal of Haematology, 1998;100:793-796). Dendritic cells (DC) are antigen...
- Natural cytotoxicity to autologous antigen-pulsed dendritic cells reported.
- Newspaper article from: Immunotherapy Weekly October 23, 2002 700+ words
...vitro differentiated dendritic cells (DCs) loaded with...published their study in British Journal of Haematology...antigen-pulsed dendritic cells in multiple myeloma...subscribe to the British Journal of Haematology...
- Monocyte-derived dendritic cells in lymphocytic leukemia characterized.
- Newspaper article from: Obesity, Fitness & Wellness Week August 21, 2004 700+ words
...study from Italy, "Dendritic cells (DCs) are the most...their study in the British Journal of Haematology...monocyte-derived dendritic cells in chronic lymphocytic...information for the British Journal of Haematology is...
- Cytomegalovirus-specific T cells stimulated using modified dendritic cells.
- Newspaper article from: Drug Week July 4, 2003 700+ words
...adenovirus-transduced dendritic cells (DC) to generate...their study in the British Journal of Haematology...CMV pp65-modified dendritic cells as stimulators...information for the British Journal of Haematology is...
