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2002 NOV 21 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have elucidated the effect of blood transfusions on the safety and efficacy of surgery to treat cervical cancer.
Nick M. Spirtos and colleagues at the Women's Cancer Center of Northern California in Palo Alto and other institutions in Buffalo, Miami, and Durham, North Carolina, evaluated the relapse and survival rates for patients who received perioperative blood transfusions.
The use of blood products during surgery had no significant effect on the risk of postoperative mortality or relapse risks, Spirtos and coauthors found.
The researchers examined data from more than 500 women who underwent surgery to treat stage I squamous cell carcinoma of the cervix. Most of these patients (77%) required at least one transfusion during surgery or shortly afterwards, according to the report.
Univariate statistical analysis suggested that transfusion did increase the risk of relapse or death, study data showed. The results of such analysis indicated that the amount of blood products transfused was significantly correlated with the likelihood of a negative outcome. ...
Source: HighBeam Research, Surgical blood transfusions do not affect relapse, survival risk.(in...