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Rotavirus vaccine could protect children from infection and related diarrhea.
2002 NOV 20 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Data gathered on infants in Guinea-Bissau, West Africa, indicated that a rotavirus vaccine could provide protection against rotavirus-related diarrhea, according to a report in the Journal of Infectious Diseases.
Thea K. Fischer and colleagues at the Projecto de Saude de Bandim in Guinea-Bissau and the University of Bergen in Norway tested for rotavirus in the stools of 200 infants in Guinea-Bissau weekly for up to 2 years.
The investigators found primary rotavirus infection occurred in 74% of the infants by the age of 2 years. The incidence of rotavirus-related diarrhea was relatively low in very young infants, increased until approximately 11 months, and then declined.
Among children younger than 3 months, incidence of diarrhea associated with rotavirus infection was 17%. The incidence rose to 60% for children 9 to 11 months old but dropped to 0% in children older than 18 months (Protective immunity after natural rotavirus infection: A community cohort study of newborn children in Guinea-Bissau, West Africa. Journal of Infectious Diseases, 2002;186(5):593-597).
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