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Dow obtains patents for production of glycoproteins in plant systems.(Brief Article)

Vaccine Weekly

| November 13, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 NOV 13 - (NewsRx.com & NewsRx.net) -- The Dow Chemical Company (NYSE:DOW) has acquired a global, exclusive assignment of patents involving significant technology in protein glycosylation for enabling the production of "mammalian-like" glycans in plants.

Many protein-based therapeutics require glycosyl groups for full functionality. To date, the dominant production method for preparing glycoproteins has involved mammalian cell cultures. The patents acquired by Dow were obtained from inventors Dr. Tatsuji Seki and Dr. Kazuhito Fujiyama, based on work completed while working at the University of Osaka, Japan.

According to Kurt Hoeprich of Dow, the company views the glycosylation technology involved in these patents as a significant event in the field of biopharmaceutical production using a plant-based approach.

By enabling the production of mammalian-like glycan structures, the new technology can potentially equip the plant-based approach to help overcome the high capital costs and production capacity limitations of current manufacturing ...

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