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Positive results reported for vaccine against potential bioterror agent.
2002 NOV 13 - (NewsRx.com & NewsRx.net) -- ID Biomedical announced encouraging results from preclinical studies of its nasally delivered proteosome-based plague pneumonia vaccine.
Mice immunized nasally with the proteosome-based plague vaccine developed high levels of antibodies in the blood, as well as in respiratory lavage fluids. These antibodies specifically recognized the major protective plague antigen. Furthermore, this vaccine elicited a high degree of protection against death in animals challenged by exposure to an aerosol containing a large inoculum of lethal plague bacteria.
Based on these results, ID Biomedical and the U.S. Army Medical Research and Materiel Command (USAMRMC) have extended their Cooperative Research and Development Agreement to continue further development of this promising vaccine candidate. Detailed results and final data are expected to be presented to the scientific community in 2003.
"These exciting results further evidence the paramount importance of nasally delivered Proteosome-based vaccines that have the ability to confer more complete protection by eliciting both a strong mucosal immune ...
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Source: HighBeam Research, Positive results reported for vaccine against potential bioterror...