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Close monitoring important to reduce risk from large-scale vaccination.

Vaccine Weekly

| November 13, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 NOV 13 - (NewsRx.com & NewsRx.net) -- In a commentary in the Journal of the American Medical Association, smallpox experts outline the potential risks associated with large-scale vaccination against the smallpox virus.

The authors wrote, "The available data from the 1950s and 1960s show that there is a risk of vaccinia transfer from a primary vaccinee to an unimmunized individual in contact with the vaccinee, but the risk is not large. This risk needs to be kept in perspective. The U.S. studies indicate that transfer of vaccinia virus from contacts that resulted in EV (eczema vaccinatum - a severe skin rash) occurred at a frequency of about 1-2 per 100,000 primary vaccinations, and the overall transmission of contact vaccinia occurred in the range of 2-6 per 100,000 primary vaccinations," the authors reported.

The authors noted that, "In all of the studies, contact vaccinia required close contact, was an unusual occurrence outside of the home, and occurred rarely as a result of hospital-related contact."

The authors noted that it is impossible to predict the likelihood of adverse ...

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Source: HighBeam Research, Close monitoring important to reduce risk from large-scale...

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