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20% of mammogram-detected cancers are in situ lesions of unknown aggressiveness.

Women's Health Weekly

| November 14, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 NOV 14 - (NewsRx.com & NewsRx.net) -- Of cancers detected by screening mammography, approximately 20% are ductal carcinoma in situ (DCIS), a noninvasive tumor contained within the walls of the breast duct, according to a multistate study led by University of California San Francisco (UCSF) researchers.

The researchers found that the likelihood of DCIS diagnosis increases with age and, overall, 1 in every 1300 screening mammograms results in a diagnosis of DCIS.

"More research is needed to understand the biology of DCIS to help us identify which disease is likely to progress to invasive cancer, and also to better tailor treatment," said Karla Kerlikowske, MD, UCSF associate professor of medicine and epidemiology and biostatistics.

Kerlikowske, who is also director of the Women Veterans Comprehensive Health Center at the SFVAMC, is among the authors of the study which was led by Virginia Ernster, PhD, UCSF professor emeritus of epidemiology and biostatistics. The findings were published in the October 16, 2002, issue of the Journal of the National Cancer Institute.

Mammography has become a very common health screening practice; an estimated 28.4 million U.S. women had mammograms in 1998. As screening mammography has become more common the incidence of diagnoses ...

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