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Urine test could make cervical cancer testing easier.
2002 NOV 14 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A novel urine screen for human papillomavirus (HPV) could make it easier to care for women infected with HIV, researchers in the United States say.
"Human immunodeficiency virus (HIV)-positive women may represent one of the fastest-growing populations at risk for acquiring cervical cancer and thus require frequent screening," explained Joeli A. Brinkman and colleagues at the Louisiana State University Health Sciences Center and Tulane University in New Orleans.
A polymerase chain reaction (PCR)-based urine assay is as reliable as standard tests for finding HPV infection, which has been linked to cervical cancer development, Brinkman and coauthors found.
The researchers compared the utility of the PCR urine screen and conventional molecular assays, which require cervical swab specimens. Positive urine and cervical swab test results had similar correlations with abnormal Pap smear results, they said.
The two types of tests were roughly 70% concordant for detecting HPV variants with the strongest links to cervical cancer development, study data showed. Cervical swab-based screens were slightly more likely than the PCR urine assay to ...
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Source: HighBeam Research, Urine test could make cervical cancer testing easier.