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Combining chemotherapy, radiation therapy improves survival odds.(cervical cancer treatment)(Brief Article)
2002 NOV 7 - (NewsRx.com & NewsRx.net) -- The updated results of a study confirm preliminary findings that chemotherapy can increase the chances of survival for some cervical cancer patients, according to a new study presented at the October 2002 American Society for Therapeutic Radiology and Oncology's Annual Meeting in New Orleans.
The study reported the findings of a randomized trial that compared extended-field radiotherapy with chemoradiation in women with locally advanced cervical carcinoma. Patients were eligible for the study if they had stages IIB-IVA, stages IB2-IIA with a tumor diameter greater than or equal to5 cm or positive pelvic lymph nodes. Four hundred three women were entered into the study between 1990 and 1997.
One group was randomized to receive extended-field radiation therapy, with 45 Gy to the pelvis and para-aortic nodes followed by low dose rate intracavitary radiation. The other group received chemoradiation, with 45 Gy pelvic radiation therapy, intracavitary radiation and three cycles of the chemotherapy drugs flourouracil and cisplatin.
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Source: HighBeam Research, Combining chemotherapy, radiation therapy improves survival...