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ACOG issues new recommendations on SERMS.( American College of Obstetricians and Gynecologists)(selective estrogen receptor modulators)
2002 NOV 7 - (NewsRx.com & NewsRx.net) -- The American College of Obstetricians and Gynecologists (ACOG) has issued new recommendations on the use of selective estrogen receptor modulators (SERMS), which are a relatively new class of synthetic estrogens that act like estrogen in certain parts of the body (such as the bones) while leaving other parts of the body unaffected.
The use of SERMS as alternative treatment to hormone replacement therapy in postmenopausal women has received increased public attention in the wake of the recent Women's Health Study results, which revealed small but significant increased risks for certain diseases in women using hormone replacement therapy.
Although SERMS are referred to collectively, their effects on different parts of the body can vary. ACOG's new practice bulletin focuses on the use of SERMS in women for their FDA-approved uses - particularly tamoxifen for reduction of breast cancer risk, and raloxifene for protection against osteoporosis.
ACOG noted that tamoxifen, originally developed to treat breast cancer patients, can be considered as a therapy to help ...
- SERMs offer safer alternative than HRT.(selective estrogen receptor...
- Magazine article from: Women's Health Weekly January 23, 2003 700+ words
...selective estrogen receptor modulators (SERMs) is emerging as a safer and more versatile...complications of menopause. Findings indicate that SERMs may be the preferred choice to HRT by mitigating...maintaining many of the therapeutic benefits. SERMs act at the level of the estrogen receptor...
- SERMs offer safer alternative than HRT.(SERMs: Selective Estrogen Receptor...
- Newspaper article from: Cancer Weekly January 21, 2003 700+ words
...selective estrogen receptor modulators (SERMs) is emerging as a safer and more versatile...complications of menopause. Findings indicate that SERMs may be the preferred choice to HRT by mitigating...maintaining many of the therapeutic benefits. SERMs act at the level of the estrogen receptor...
- SERMs: The Year in Review.
- Magazine article from: OB GYN News E. Nachtigall, Dr Lila August 1, 2000 700+ words
...osteoporosis. Most recently, selective estrogen receptor modulators (SERMs) have entered into the consideration of therapeutic options for postmenopausal women. The exact role of SERMs in menopausal and postmenopausal health remains to be defined...
- SERMs and Skeletal Health: The Prevention and Treatment of Osteoporosis.
- Magazine article from: OB GYN News Lindsay, Dr Robert August 1, 2000 700+ words
...replacement therapy (HRT), selective estrogen receptor modulators (SERMs), bisphosphonates, and calcitonin. "Essentially, all the...not want or cannot tolerate HRT. In addressing the role of SERMs in osteoporosis, Dr Lindsay focused on data from a study of...
- Other active and safer SERMs and aromatase inhibitors need to be developed.
- Newspaper article from: Clinical Oncology Week June 2, 2003 700+ words
...NewsRx.com & NewsRx.net) -- Other active and safer SERMs and aromatase inhibitors need to be developed. "Clinical trials...are most likely to gain benefit, and the development of other SERMs and aromatase inhibitors which might be more active and have...
- Combined therapy with SERMs and estrogen show promise in rat studies.
- Newspaper article from: OBGYN & Reproduction Week November 24, 2003 700+ words
...Fernand Labrie, MD, and his colleagues suggests that the next generation of menopausal therapy may lie in a combination of SERMs and estrogen, with the SERM preventing the potential risk of breast cancer caused by the estrogen. The researchers treated...
- Expanding Horizons: SERMs, Cardiovascular Disease, and Cognitive Function in...
- Magazine article from: OB GYN News W. Stovall, Dr Dale August 1, 2000 700+ words
...selective estrogen receptor modulators (SERMs) has yielded provocative but inconsistent...function. The evidence to date indicates that SERMs are associated with a cardioprorective...events. Data regarding the effects of SERMs on cognitive function and central nervous...
- Testing Continues on SERMs for Prevention of Bone Loss in Osteoporosis And...
- Press release article from: PR Newswire October 9, 2000 700+ words
...continue to develop Selective Estrogen Receptor Modulators (SERMs). SERMs behave as estrogen in some tissues -- increasing bone...preventing the risk of uterine and breast cancer. Using SERMs to address the loss of bone mass, while lowering lipids...
