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Clot-busting therapy appears safe for menstruating women.(tissue plasminogen activator)
2002 NOV 7 - (NewsRx.com & NewsRx.net) -- In emergency stroke treatment, the clot buster tissue plasminogen activator (tPA) can be safely given to women who are menstruating.
However, it must be used with caution in those with a history of dysfunctional uterine bleeding, according to the first report of its kind published in the October 2002 issue of Stroke.
The drug is the only U.S. Food and Drug Administration-approved treatment for acute stroke. Research indicates that tPA can reduce permanent disability if given within 3 hours of the onset of stroke symptoms.
Currently, women who are menstruating at the time of stroke may not receive tPA because the drug could cause excessive bleeding, said lead author Theodore H. Wein, MD, assistant professor of neurology and neurosurgery at McGill University in Montreal, Canada.
Wein reported that he gave tPA to a 40-year-old menstruating woman having a stroke. The woman had lost part of her language abilities and was paralyzed on her right side.
"We explained the risks of tPA, as well as the possibility that if bleeding did occur the worst-case scenario would be that she may need an emergency hysterectomy," said Wein. "She did have increased menstrual flow and required a blood transfusion but, ...
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