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Low folic acid levels linked with increased risk of early spontaneous abortion.
2002 NOV 7 - (NewsRx.com & NewsRx.net) -- Women with low folic acid levels are at a significantly increased risk of having an early, naturally occurring termination of their pregnancy, according to an article in the Journal of the American Medical Association.
According to background information in the article, both folate deficiency and folic acid supplements have been reported to increase the risk of spontaneous abortion, which refers to the naturally occurring termination of a pregnancy - end of the pregnancy with expulsion of the fetus from the woman's body - before the 20th week of pregnancy. The authors wrote that the results of previous studies are inconclusive, and measurements of folate have not been available in all studies.
Lena George, MD, of the Huddinge University Hospital, Karolinska Institute, Stockholm, Sweden, and colleagues conducted a study to determine the association between plasma folate levels and the risk of spontaneous abortion. The study was conducted between January 1996 to December 1998 in Sweden, where folic acid food fortification has not been introduced. The research included 468 women who had a spontaneous abortion, and 921 controls. Plasma folate measurements were taken at 6 to 12 gestational weeks.
The authors found that compared with women with plasma folate levels between 2.20 and 3.95 ng/mL, women with low (less than or equal to2.19 ng/mL) ...
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Source: HighBeam Research, Low folic acid levels linked with increased risk of early spontaneous...