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Development of oral biological defense vaccines initiated.
2002 NOV 6 - (NewsRx.com & NewsRx.net) -- DOR BioPharma, Inc., (DOR) announced that it has initiated a program to produce orally administered vaccines to protect against exposure to biological agents that can potentially be used in bioterrorist attacks.
The initial candidate vaccine is against ricin toxin, a highly potent biological toxin that is relatively easy to produce, store, and disperse and therefore a candidate for bioterrorism.
DOR stated, "Orally administered nonlive vaccines may represent a preferred method of protecting our troops and population from certain biological threats given their potential ease of administration and distribution, low cost and speed of production, prolonged shelf-life, mucosal and systemic protection and avoidance of use of live pathogens."
Through its interest in its Innovaccines joint venture, DOR has an exclusive license to dominant intellectual property covering the oral delivery of encapsulated nonlive vaccines, including U.S. Patent Nos. 6,024,983; 5,942,252; 5,853,763; 5,820,883; 5,814,344; and 5,811,128 as well as European patents EP 0 266 119 and EP 0 333 523.
According to results recently published by researchers at the United ...
- DOR BioPharma Announces Positive Phase I Results of RiVax(TM), its Vaccine...
- Press release article from: Business Wire January 30, 2006 700+ words
...TM), a recombinant vaccine against ricin toxin, that has been completed by investigators...antibodies in humans that neutralize ricin toxin. The outcome of the study will be published...RiVax(TM) marks the first time a ricin toxin vaccine has ever been clinically tested...
- DOR BioPharma, Inc. Announces Positive Interim Results from Phase I Clinical...
- Press release article from: Business Wire June 15, 2005 700+ words
...RiVax(TM), its vaccine against ricin toxin. The Phase I clinical trial of RiVax(TM) represents the first ricin toxin vaccine ever to be clinically tested...This is the first indication that a ricin toxin vaccine elicits immune responses...
- Field Test for Ricin Toxin Available from Osborn Scientific; Company Confirms...
- Press release article from: Business Wire August 21, 2002 700+ words
...that its environmental test kit for ricin toxin is available for first responder units...Iraq laboratory suspected of producing ricin toxin, a byproduct of the widely available...OSG product was designed to identify ricin toxin in quantities that approximate one...
- DOR BioPharma Awarded Two Grants Totaling $5.3 Million to Advance Ricin Toxin...
- Press release article from: Business Wire September 29, 2006 700+ words
...TOTALING $5.3 MILLION TO ADVANCE RICIN TOXIN AND BOTULINUM TOXIN VACCINE PROGRAMS...TM], a recombinant vaccine against ricin toxin. The second grant of approximately...personnel to administer the vaccine. About Ricin Toxin and Botulinum Toxin Ricin toxin is a...
- DOR BioPharma Reports Initiation of Dosing of Ricin Vaccine - RiVax - in Phase...
- Press release article from: Business Wire February 7, 2005 700+ words
...vaccine designed to protect against ricin toxin. After having successfully passed prerequisite...evaluations, RiVax(TM) (recombinant ricin toxin vaccine) is the first ricin vaccine...effectiveness in protecting the animals from ricin toxin exposure. Given its FDA-approved...
- Vaccine Researchers Combat Biothreat Agents; Preclinical Safety Testing Aims to...
- Press release article from: Business Wire July 5, 2005 700+ words
...for protection against exposure to the ricin toxin, a potential biothreat agent. In September...which is a nontoxic modification of the ricin toxin, from the University of Texas Southwestern...trial of RiVax, which is the first ricin toxin vaccine to be clinically tested in humans...
- Dor BioPharma announces initiation of second human clinical trial for RiVax,...
- News wire article from: Chemical Business Newsbase August 7, 2008 700+ words
...induce protection against exposure to ricin toxin, a category B biothreat. This new...antibodies in humans that neutralized ricin toxin in tissue culture and in mice. The...immunogenicity data is anticipated in 1H 2009. Ricin toxin is thought to be a bioterror threat...
- DOR BioPharma in CRADA for ricin toxin vaccine research.
- Newspaper article from: Pharma Marketletter November 26, 2007 700+ words
...RiVax, the company's preventive vaccine against ricin toxin. The CRADA will be carried out at the Division...important in inducing human immune responses to ricin toxin. Ricin toxin is an easy to manufacture toxin that poses a serious...
- Dor BioPharma reports initiation of dosing of ricin vaccine (RiVax) in Phase I...
- News wire article from: Asia Africa Intelligence Wire February 7, 2005 700+ words
...vaccine, designed to protect against ricin toxin. After having successfully passed prerequisite...efficacy evaluations, RiVax (recombinant ricin toxin vaccine) is the first ricin vaccine...effectiveness in protecting the animals from ricin toxin exposure. Obtained from castor beans...
- Company announces new developments on ricin toxin vaccine.(DOR BioPharma, Inc.)
- News wire article from: Bioterrorism Week February 3, 2003 700+ words
...bioterrorist weapons. Lung damage caused by inhalation of ricin toxin is quick and irreversible. Even relatively small-scale...candidate consists of only one of the two subunits of the ricin toxin which has been genetically engineered to eliminate both its...
Source: HighBeam Research, Development of oral biological defense vaccines initiated.