AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
HPV16 antibodies cause regression of cervical neoplasia.
2002 NOV 6 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Neutralizing antibodies against human papillomavirus 16 (HPV16) appear to cause regression of cervical intraepithelial (CIN) lesions and may even eliminate lesions in some cases.
Kei Kawana and colleagues at the University of Tokyo assigned 76 women to one of four categories based upon their cervical pathology, normal (n=7), CIN1 (n=37), CIN2 or CIN3 (n=19), or cervical cancer (n=13). Serum samples from the subjects were tested for neutralizing antibodies against HPV16 using HPV16-pseudovirions.
Women with normal cervical pathology were significantly more likely (p
The amount of HPV DNA was significantly lower in women with neutralizing antibodies compared with women who did not have neutralizing antibodies (p=0.05).
"The neutralizing antibodies seem to have a role in deterring HPV-related cervical lesions from progressing to CIN2/3 by inhibiting the infection with de novo replicated HPV," reported Kawana and associates. "This study further suggests that HPV vaccine to induce the neutralizing antibodies may be effective in eliminating CIN lesions, especially in the neutralizing-antibody-negative cases." (Neutralizing antibodies against oncogenic human papillomavirus as a possible determinant of the fate of low-grade cervical ...
- Neutralizing antibodies after infection with dengue 1...
- Magazine article from: Emerging Infectious Diseases Guzman, Maria G. Alvarez, Mayling Rodriguez-Roche, Rosmari Bernardo, Lidice Montes, Tibaire Vazquez, Susana Morier, Luis Alvarez, Angel Gould, Ernest A. Kouri, Gustavo Halstead, Scott B. February 1, 2007 700+ words
...mean titer of homologous DENV-1 neutralizing antibodies and a significant decrease in...phenotypic changes in heterotypic viral neutralizing antibodies in the predicted direction. This...presence or absence of heterotypic neutralizing antibodies might contribute to severity of...
- Neutralizing antibodies - and what they mean. (in multiple sclerosis care)
- Magazine article from: Inside MS March 22, 1997 700+ words
...The culprit appears to involve neutralizing antibodies, which this portion of the group...18 months. The appearance of neutralizing antibodies is associated with this change...While some people lost their neutralizing antibodies, and a few others developed them...
- Studies Show COPAXONE(R) Does Not Generate Neutralizing Antibodies; Of the...
- Press release article from: PR Newswire March 27, 2003 700+ words
...immunomodulating drugs developed neutralizing antibodies that would affect the drug's...while others are neutralizing. Neutralizing antibodies in the three interferon-beta...The article concluded that, "Neutralizing antibodies can appear early during the course...
- Neutralizing antibodies and sin nombre virus RNA after recovery from hantavirus...
- Magazine article from: Emerging Infectious Diseases Ye, Chunyan Prescott, Joseph Nofchissey, Robert Goade, Diane Hjelle, Brian March 1, 2004 700+ words
...likely to exhibit a high titer of neutralizing antibodies against Sin Nombre virus (SNV...patients retain high titers of neutralizing antibodies long after recovery from SNV infection...had markedly higher titers of neutralizing antibodies on admission than did those patients...
- Neutralizing antibodies to IFN beta-1b therapy for relapsing-remitting MS may...
- Newspaper article from: Biotech Week January 14, 2004 700+ words
...com & NewsRx.net) -- Neutralizing antibodies (NAbs)to IFN beta-1b therapy...approaches to assessing the effects of neutralizing antibodies - IFN beta-1b in the pivotal...Proteomics, Neurology, Risk Factor, Neutralizing Antibodies, Interferon Beta-1b Therapy...
- Virus-cross-HIV-1-neutralizing antibodies induced by in vivo expression system.
- Newspaper article from: AIDS Weekly April 7, 2003 700+ words
...immunodeficiency virus type 1-neutralizing antibodies were induced in small animals...have studied the induction of neutralizing antibodies by in vivo expression of the human...cross-reactive, primary virus-neutralizing antibodies (donor of reference serum, HIV...
- Antigen engineering promotes induction of HIV-neutralizing antibodies.
- Newspaper article from: AIDS Vaccine Week January 19, 2004 700+ words
...induction of HIV-neutralizing antibodies. According to a study...Understanding how neutralizing antibodies recognize HIV could...broadly HIV-1-neutralizing antibodies b12, 2G12 and 2F5...
- FDA Approves Labeling Change for Biogen's Avonex(R) (Interferon Beta-1a) to...
- Press release article from: PR Newswire November 14, 2002 700+ words
...significance of neutralizing antibodies to AVONEX is unknown...patients developing neutralizing antibodies." All therapeutic...antibodies, called neutralizing antibodies, can attach to...used by pregnant women. People with...
Source: HighBeam Research, HPV16 antibodies cause regression of cervical neoplasia.