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Raloxifene increases level of protein believed to inhibit estrogen-sensitive breast cancer.(Abstract)
2002 OCT 10 - (NewsRx.com & NewsRx.net) -- In a study supported by Eli Lilly and Co. and published in the September 2002 issue of Fertility and Sterility, researchers at Boston's Beth Israel Deaconess Medical Center, the Medical Center for Women's Clinical Research in San Diego and the University of South Florida evaluated the effect of raloxifene, a drug often prescribed to treat and prevent postmenopausal osteoporosis, on the levels of several hormones and proteins in postmenopausal women.
Ninety-three women between the ages of 42 and 80 who were at least 2 years past menopause were enrolled in the study and randomly assigned to either the raloxifene or the placebo group. Eighty-nine completed the study: 46 from the raloxifene group and 43 from the placebo group.
Each participant was evaluated at the start and at the completion of the 3-month study for serum levels of estrogen, estrone, sex steroid-binding globulin, thyroxine-binding globulin, and follicle-stimulating hormone ...
- Dietary [beta]-Tocopherol and Linoleic Acid, Serum Insulin, and Waist...
- Magazine article from: The Journal of Nutrition Nayeem, Fatima; Nagamani, Manubai; Anderson, Karl E; Huang, Yafei; Grady, James J; Lu, Lee-Jane W June 1, 2009 700+ words
...circulating sex hormone-binding globulin (SHBG) are implicated in the etiology of sex steroid-related pathologies...Introduction Sex hormone-binding globulin (SHBG) , a glycoprotein...on cell membranes in sex steroid-responsive organs...
- Sex Hormone Levels Linked to Fractures in Men; Testing for estradiol,...
- News wire article from: Consumer Health News (English) August 14, 2009 700+ words
...with low levels of estradiol or high levels of sex hormone binding globulin (SHBG) were more likely to suffer osteoporotic fractures...estradiol in the blood. It's known to reduce circulating sex steroid concentrations and has previously been linked with fracture...
- Dietary [beta]-Tocopherol and Serum Concentrations of Sex Hormone-Binding...
- Magazine article from: The Journal of Nutrition Chow, Ching Kuang; Lu, Lee-Jane; Nayeem, Fatima; Anderson, Karl E October 1, 2009 700+ words
...independent predictors of the circulating sex hormone-binding globulin (SHBG) and suggest that increased consumption of these...and waist circumference predict circulating sex hormone-binding globulin in premenopausal women. J Nutr. 2009;139:1135-42...
- Discontinuing OCs may not lower SHBG in some women.(Women's Health)(oral...
- Magazine article from: Family Practice News Lesney, Mark S. April 15, 2006 700+ words
...dysfunction maintained elevated levels of sex hormone-binding globulin even after they discontinued use of oral contraceptives...colleagues. In a retrospective study of sex hormone-binding globulin (SHBG) levels before and after discontinuation of oral...
- thyroxine-binding globulin
- Reference information from: The Mosby Medical Encyclopedia October 1, 1996 700+ words
The Mosby Medical Encyclopedia 10-01-1996 thyroxine-binding globulin, a plasma protein that binds with and transports thyroxine in the blood. The ideas, procedures and suggestions contained in...
- Metabolic Profile and Sex Hormone Binding Globulin (SHBG) in Different...
- Magazine article from: Physiological Research Kosková, I; Petrásek, R; Vondra, K; Dusková, M; Stárka, L May 1, 2009 700+ words
...X raises with age, especially in postmenopausal women (Park et al. 2003) and hyperandrogenemia and low sex hormone binding globulin (SHBG) are frequently found in such patients (Reinecke et al. 2002). Study on 26 Czech women with impaired glucose...
- Levels of SHBG, sex-steroid hormones correlate with volume in African Americans.
- Newspaper article from: Cancer Weekly February 4, 2003 700+ words
...the associations of sex-steroid hormones and benign...alcohol, and endogenous sex-steroid hormones with prostate...and sex hormone-binding globulin (SHBG). Multivariable...SHBG and endogenous sex-steroid hormones are correlated...
- Sex steroid receptors in human skin differentially localized.
- Newspaper article from: Angiogenesis Weekly May 28, 2004 700+ words
...com & NewsRx.net) -- Sex steroid receptors in the human skin are differentially localized. "Sex steroid hormones are involved in regulation...the differential localization of sex steroid receptors in human skin should be...
Source: HighBeam Research, Raloxifene increases level of protein believed to inhibit...