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Study results indicate tb revaccination not warranted in japanese children.(Brief Article)

Vaccine Weekly

| October 09, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 OCT 9 - (NewsRx.com & NewsRx.net) -- An assessment of the economics of revaccinating Japanese children for tuberculosis finds the practice is unnecessary.

"Bacillus Calmette-Guerin (BCG) revaccination has been implemented in Japan among tuberculin-negative first grade primary and first grade junior high school students for decades," M. Rahman and colleagues, Kyoto University. "Controversies regarding the effectiveness of BCG revaccination and low incidence of tuberculosis (TB) among Japanese children prompted this study."

The researchers performed "cost-effectiveness and cost-benefit analyses...for a cohort of schoolchildren who underwent revaccination during 1996. The study population was a hypothetical cohort comprising 1.35 million first grade primary school and 1.51 million first grade junior high school students enrolled in 1996 at locations throughout Japan.

"Assuming 50% vaccine efficacy for revaccination, a 10-year duration of protection, and 5% annual discount rate, we calculated the total hypothetical number of TB cases averted, the cost and number of immunizations per TB case averted, and the benefit-cost ratio for the program," explained Rahman and colleagues.

Rahman and coworkers published the results of their study in Preventive Medicine (Is bacillus Calmette-Guerin revaccination necessary for ...

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