Studies: Promensil reduces frequency, severity of hot flashes.(Brief Article)

2002 OCT 3 - (NewsRx.com & NewsRx.net) -- Two new studies demonstrate that Promensil is effective at reducing the frequency and severity of hot flashes.

The studies were published in the current issues of The Female Patient and Maturitas/The European Menopause Journal.

Promensil is a high quality dietary supplement made from red clover and standardized according to pharmaceutical grade good manufacturing practice (GMP) procedures.

This study shows that the commercially available dose (40 mg per day) of Promensil reduced hot flashes by nearly 50% (48.5), while a placebo used in a control group of patients reduced hot flashes by only about 10% (10.5).

"This study demonstrates that dietary supplementation with red-clover derived isoflavones (Promensil) is an effective alternative for symptomatic relief of vasomotor symptoms in postmenopausal women, reducing both the average daily frequency and severity of hot flushes," said Arturo Jeri, MD, director, climacteric unit, Institute of Gynaecology and Reproduction, Lima, Peru, and author of the study. "Many botanical and nutritional therapies are offered for use during menopause, however Promensil has the clinical evidence supporting a favorable risk-benefit profile."

The double-blinded study reviewed data on 30 healthy, nonvegetarian women who had been postmenopausal for more than 1 year. The patients had not used Hormone Replacement Therapy (HRT), soy, or other estrogen-active plant products for at least 16 weeks prior to the study. The group was divided into 2 equal groups of 15 patients.

The study used nonvegetarian women to avoid potential biasing from higher than usual consumption of soy and other legumes, often seen in vegetarian women. Severity of symptoms was self-measured by patients on a scale of zero (no symptoms) to three (severe, interferes with normal activities.)