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Prospects for edible vaccines limited, but still promising.(Brief Article)

Vaccine Weekly

| October 02, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 OCT 2 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "The use of edible plants for the production and delivery of vaccine proteins could provide an economical alternative to fermentation systems.

"Genes encoding bacterial and viral antigens are faithfully expressed in edible tissues to form immunogenic proteins. Studies in animals and humans have shown that ingestion of transgenic plants containing vaccine proteins causes production of antigen-specific antibodies in serum and mucosal secretions," wrote H.S. Mason and colleagues, Boyce Thompson Institute of Plant Research.

"In general, the technology is limited by low expression levels for nuclear-integrated transgenes, but recent progress in plant organelle transformation shows promise for enhanced expression."

Mason et al. published their study ...

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Source: HighBeam Research, Prospects for edible vaccines limited, but still promising.(Brief...

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