AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Weight controlling protein may be source of fatigue in chronic hepatitis C.(leptin)(Brief Article)
2002 SEP 26 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Scientists think leptin, a protein thought to control weight, may be the source of some fatigue in patients, especially females, who have chronic hepatitis C.
Doctors in France have undertaken a study examining fatigue in men and women diagnosed with chronic hepatitis C. What they found was that fatigue is particularly pronounced in those patients, and that leptin levels, thought to regulate weight and energy usage, may contribute to that fatigue.
Their study included 78 patients with chronic hepatitis C, 13 patients with primary biliary cirrhosis, and 22 healthy controls. Each person was measured for several components of body chemistry and physiology, and was assessed for fatigue based on the answers they provided on fatigue impact scale (FIS) questionnaires.
Approximately half of the patients with chronic hepatitis C reported that fatigue was a prominent effect of being HCV-positive.
Chronic hepatitis C patients, particularly the females, had much higher fatigue scores than did healthy controls.
In addition, leptin levels were elevated in chronic hepatitis C patients, and after correction for fat mass, those levels significantly associated with fatigue scores, T. Piche and colleagues, CHU de Nice, Nice, France said (Fatigue is associated with high circulating leptin levels in chronic hepatitis C. Gut, September 2002;51(3):434-439).
"This ...
- High leptin levels associate with fibrosis severity in chronic hepatitis C.
- Newspaper article from: Proteomics Weekly March 15, 2004 700+ words
...net) -- High leptin levels associate with fibrosis severity in chronic hepatitis C. According...patients with chronic hepatitis C (CHC). We...associated with high leptin levels in chronic hepatitis C. J Viral Hepatitis...
- Leptin Levels Remain Stable in Patients with Steatosis and Liver Fibrosis.
- Newspaper article from: Hepatitis Weekly January 15, 2001 700+ words
...investigators, leptin levels in the chronic hepatitis C patients...study are: * Leptin levels are no higher in chronic hepatitis C patients...steatosis * Leptin levels do not associate...fibrosis in chronic hepatitis C patients...
- Serum leptin levels in rheumatoid arthritis and relationship with disease...
- Magazine article from: Southern Medical Journal Gunaydin, Rezzan Kaya, Taciser Atay, Aysenur Olmez, Nese Hur, Aysel Koseoglu, Mehmet October 1, 2006 700+ words
...study was performed to evaluate serum leptin levels in rheumatoid arthritis (RA) patients...assay was used for measuring serum leptin levels (ng/mL). Serum TNF-[alpha...subjects (P > 0.05). Serum leptin levels were higher in RA (P = 0.000...
- High leptin levels predict renewed weight loss in anorexic patients.
- Newspaper article from: Biotech Week July 14, 2004 700+ words
...amp; NewsRx.net) -- High serum leptin levels subsequent to weight gain predict renewed...repeatedly been shown that high serum leptin levels at target weight ensue from therapeutically...It was hypothesized that elevated leptin levels may be an important factor underlying...
- Circulating leptin levels in rats are independent of tissue leptin expression.
- Newspaper article from: Obesity, Fitness & Wellness Week March 22, 2003 700+ words
...associated differences in circulating leptin levels in rats are independent of tissue leptin...a study from Spain, "Circulating leptin levels are higher in women than in men. The...and the relationship with circulating leptin levels." "Adult male and female Wistar...
- Fish-rich tribal diet linked with low leptin levels.
- Newspaper article from: Heart Disease Weekly August 4, 2002 700+ words
...have consumed enough food. High leptin levels have been associated with obesity...clearly associated with increased leptin levels. "Regardless of body fat or body mass index (BMI), leptin levels were substantially lower among the...
- Thyrotropin-releasing hormone reduces leptin levels in children and adolescents.
- Newspaper article from: Obesity, Fitness & Wellness Week October 23, 2004 700+ words
...hormone administration reduces plasma leptin levels in infants, children, and adolescents...standard TRH stimulation test) on plasma leptin levels in infants, children, and adolescents. Plasma leptin levels were analyzed with regard to age...
- Leptin levels associated with insulin resistance and insulin secretion.
- Newspaper article from: Diabetes Week July 21, 2003 700+ words
...NewsRx.com & NewsRx.net) -- Leptin levels were associated with insulin resistance...study, we evaluate the associations of leptin levels with insulin secretion and insulin...scientists in Belgium report. "Fasting leptin levels, HbA[subscript]1c, glucose...
