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Hip or thigh yield comparable vaccine protection in immunized infants.(Brief Article)
2002 SEP 25 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - A new study indicates vaccinating infants on the hip (ventrogluteal area) or on the front side of the thigh (anterolateral) with hepatitis B virus (HBV) vaccine are equally effective for stimulating protection against viral infection although some adult studies have indicated otherwise.
In the pediatric study, which was performed in a town in New South Wales, researchers at Monash University of Melbourne, Victoria, Australia enrolled 200 infants to randomly receive three doses of Engerix-B HBV vaccine at the ventrogluteal site or the anterolateral site on a commonly prescribed vaccination schedule.
Later, they sampled the infants' blood to measure the antibody titers that formed after vaccination, administering subsequent immunizations to those infants who failed to develop protective titers after the third vaccine dose.
Four to 6 weeks after the last dose was administered, I. Cook and colleagues were able to check antibody titers in 177 babies. Eighty-seven of those had received injections at the ventrogluteal site, and the remainder had been vaccinated in the anterolateral thigh site.
Antibody response rates signaling effective vaccination at the ventrogluteal and anterolateral thigh sites were 96.6% and 93.2%, respectively, within the two infant groups. ...
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Source: HighBeam Research, Hip or thigh yield comparable vaccine protection in immunized...