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Lack of social support reinforces tumor factor in women with ovarian cancer.(Brief Article)
2002 SEP 19 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical - The lack of sufficient social support may cause some women with ovarian cancer to produce abnormal levels of a growth factor that spurs cancer growth.
Doctors announced in the journal Cancer that social well-being can have an affect on cell stimulation factors in women with ovarian cancers. Strengthening social support systems might be one way to stem cancer progression in women with ovarian carcinoma, although more studies are needed.
The clinical study was conducted by medical researchers in the Departments of Psychology and Obstetrics and Gynecology at the University of Iowa in Iowa City. There, investigators examined vascular endothelial growth factor expression in the context of tumorigenesis and patient behaviors in 24 women with ovarian cancer and 5 women with benign pelvic growths. Behavioral factors can control the synthesis of vascular endothelial growth factor (VEGF), according to the researchers.
"VEGF is a key cytokine that is capable of stimulating tumor angiogenesis, and it has been associated with poorer survival in patients with ovarian carcinoma," Susan K. Lutgendorf and colleagues explained.
During the study, Lutgendorf and associates tested the women for presurgical levels of serum VEGF and administered them psychological surveys.
They reported finding lower levels of growth factor in cancer patients who were socially content (Vascular endothelial growth factor and social support in patients with ...
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Source: HighBeam Research, Lack of social support reinforces tumor factor in women with ovarian...