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Patients may benefit from revolutionary womb transplant surgery.(Brief Article)
2002 SEP 19 - (NewsRx.com & NewsRx.net) -- Revolutionary surgery in womb transplants may give hope to patients with fertility problems. Infertility is an increasing problem in the western world and it is estimated that around 15% of all couples are infertile.
Most causes of infertility are today treatable by in vitro fertilization (IVF) and sperm injection (ICSI), but infertility due to a hysterectomy or womb malformation is not treatable. Uterine infertility can be caused by injury, congenital conditions, or hysterectomy. Even though these patients in most cases have functioning ovaries they have no chance of carrying their own genetic child.
Now new research published in the Journal of Endocrinology may give hope to this group of patients. A team led by Dr. Mats Brannstrom at the Sahlgrenska Academy at Goteborg University in Sweden have carried out the first-ever uterine transplantation in mice which has led to successful pregnancy in the transplanted uterus.
Brannstrom and his team, including the PhD student Randa Racho El-Akouri, took a uterus from a donor and transplanted it alongside the recipient's uterus. This enabled the researchers to compare the function of both wombs within the same animal. The team transferred the same amount of embryos to the donor and recipient uterus, which gave three fetuses in the recipient uterus and one in the donor uterus. The pregnancies were then halted for further investigation.
"We are delighted with the results of this study as we can use this model to study physiological aspects of pregnancies in the transplanted uterus, rejection mechanisms and postnatal ...
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