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Cell stimulation factor a force in infertility and endometriosis.(macrophage migration inhibitory factor)
2002 SEP 12 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Women with endometriosis may be plagued by increased levels of a cell factor that stimulates angiogenesis, or neovascularization in the abdominal cavity.
Several studies have indicted angiogenesis in the pathogenesis of endometriosis, and the cell factor is associated with angiogenic activity. Patients contending with endometriosis-related infertility appear to produce even higher levels of the factor, which is known as macrophage migration inhibitory factor (MIF).
Medical researchers in Canada have studied MIF levels in the peritoneal fluid of females with endometriosis, other women with endometriosis-associated fertility, and healthy women without endometriosis.
"The study demonstrated the presence of MIF in the peritoneal fluid and a 238% increase of MIF levels in women with endometriosis as compared with healthy women," reported R. Kats and colleagues of the Center for Research at the Hospital of St. Francis Espinay in Quebec City, Canada.
MIF levels were significantly higher in infertile women with endometriosis than in the other two groups of women (Marked elevation of macrophage migration inhibitory factor in the peritoneal fluid of women with endometriosis. Fertility and ...
- Macrophage migration inhibitory factor in ocular fluids of patients with...
- Magazine article from: British Journal of Ophthalmology Taguchi, Chikako Sugita, Sunao Tagawa, Yoshitsugu Nishihira, Jun Mochizuki, Manabu November 1, 2001 700+ words
...To investigate the levels of macrophage migration inhibitory factor (MIF) in intraocular...pathophysiology of ocular inflammation. Macrophage migration inhibitory factor (MIF) was originally...lymphocyte derived factor to inhibit macrophage migration. [1] Recent investigations have...
- Macrophage migration inhibitory factor increased in obesity.
- Newspaper article from: Biotech Week December 29, 2004 700+ words
...com & NewsRx.net) -- Plasma concentration of macrophage migration inhibitory factor (MIF) and MIF mRNA are increased...Endocrinology and Metabolism (Increased plasma concentration of macrophage migration inhibitory factor (MIF) and MIF mRNA in mononuclear...
- Macrophage migration inhibitory factor key to vascularity of glioblastoma.
- Newspaper article from: Angiogenesis Weekly February 28, 2003 700+ words
...involved in this process is of major clinical interest." "Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine released...in American Journal of Pathology (Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial...
- Macrophage migration inhibitory factor key to vascularity of...
- Newspaper article from: Cancer Weekly February 25, 2003 700+ words
...involved in this process is of major clinical interest." "Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine released...in American Journal of Pathology (Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial...
- Expression of macrophage migration inhibitory factor in diffuse systemic...
- Magazine article from: Annals of the Rheumatic Diseases Selvi, E Tripodi, SA Catenaccio, M Lorenzini, S Chindamo, D Manganelli, S Romagnoli, R Ietta, F Paulesu, L Miracco, C Cintorino, M Marcolongo, R May 1, 2003 700+ words
...with the diffuse form of systemic sclerosis (dSSc), macrophage migration inhibitory factor (MIF) production is dysregulated...scleroderma tissue remodelling. ********** Macrophage migration inhibitory factor (MIF) was initially identified as...
- Cytokine tied to depression in pregnant women: macrophage migration inhibitory...
- Magazine article from: Family Practice News Goldman, Erik May 1, 2005 700+ words
NEW YORK -- Macrophage migration inhibitory factor, a newly characterized cytokine that...treatment for major depression have markedly higher levels of macrophage migration inhibitory factor (MIF) than do nondepressed pregnant...
- Dengue virus infection induced NF-[kappa]B-dependent macrophage migration...
- Magazine article from: American Journal of Infectious Diseases Chen, Lien-Cheng Shyu, Huey-Wen Lei, Huan-Yao Chen, Shun-Hua Liu, Hsiao-Sheng Lin, Yee-Shin Yeh, Trai-Ming January 1, 2008 700+ words
...severe dengue hemorrhage fever and dengue shock syndrome. Macrophage migration inhibitory factor (MIF) is a cytokine that plays an...dependent but serotype and FcR-independent manner [7]. Macrophage migration inhibitory factor (MIF) is a cytokine important in...
- AVANIR Acquires Macrophage Migration Inhibitory Factor Technology for The...
- Press release article from: PR Newswire August 9, 2001 700+ words
...DIEGO, Aug. 9 /PRNewswire/ -- AVANIR Pharmaceuticals (Amex: AVN) announced today that it has acquired a macrophage migration inhibitory factor (MIF) technology from the Ciblex Corporation. The asset acquisition provides AVANIR with...
- Genmab licenses MIF from Cytokine PharmaSciences.(macrophage migration...
- Newspaper article from: Pharma Marketletter November 27, 2006 700+ words
Danish biotechnology company Genmab AS says that it has licensed rights to a macrophage migration inhibitory factor (MIF) receptor from Cytokine PharmaSciences of the USA. MIF is a pro-inflammatory cytokine that is known...
- Ciblex Scientists Identify Small Molecule Inhibitor of Macrophage Migration...
- Press release article from: PR Newswire July 13, 2000 700+ words
...Scientists at Ciblex Corporation announced today that they have identified a small molecule inhibitor of Macrophage Migration Inhibiting Factor (MIF), CBX21404, which is biologically active in mice. This is a critical first step in...
Source: HighBeam Research, Cell stimulation factor a force in infertility and...