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Screening protocol developed to identify postmenopausal women with IGT or type 2 diabetes.(impaired glucose tolerance)
2002 SEP 12 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A screening protocol for postmenopausal women that combines fasting plasma glucose (FPG) results with body mass index (BMI) measurements identified most of the women with impaired glucose tolerance (IGT) and almost all of the women with type 2 diabetes,
Mithat Erenus and colleagues at the Marmara University School of Medicine in Istanbul conducted fasting plasma glucose (FPG) tests followed by oral glucose tolerance testing (OGGT) in 100 consecutive postmenopausal women. The investigators also collected baseline measurements of serum lipids and insulin levels in the women.
A cutoff value of 98 mg/mL for FPG (71% sensitivity and 76% specificity) was optimal for detecting IGT. A 96% sensitivity could be achieved by the addition of body mass index (BMI) screening with a cutoff of 26.5 kg/m[superscript]2, but the specificity dropped to 47%,
By using the combination FPG/BMI screening process, Erenus and associates were able to identify 94% of the women with IGT and all of the women with type 2 diabetes (Should we consider performing oral glucose tolerance tests more frequently in postmenopausal women for optimal screening of impaired glucose tolerance? Menopause - Journal of the North American Menopause Society, 2002;9(4):296-301).
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