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Promensil reduces frequency and severity of hot flashes.
2002 SEP 12 - (NewsRx.com & NewsRx.net) -- Two new studies offer women who are looking for natural relief from symptoms associated with menopause clinical proof that Promensil is effective at reducing the frequency and severity of hot flashes. The studies were published in the current issues of the Female Patient and Maturitas/The European Menopause Journal.
Promensil is a dietary supplement made from red clover and standardized according to pharmaceutical grade Good Manufacturing Practice (GMP) procedures.
This study shows that the commercially available dose (40 mg per day) of Promensil reduced hot flashes by 48.5%, while a placebo used in a control group of patients reduced hot flashes by only about 10.5%.
"This study demonstrates that dietary supplementation with red-clover derived isoflavones [Promensil] is an effective alternative for symptomatic relief of vasomotor symptoms in postmenopausal women, reducing both the average daily frequency and severity of hot flushes," said Arturo Jeri, MD, director, climacteric unit, Institute of Gynaecology and Reproduction, Lima, Peru, and author of the study. "Many botanical and nutritional therapies are offered for use during menopause; however Promensil has the clinical evidence supporting a favorable risk-benefit profile."
The double-blinded study reviewed data on 30 healthy, nonvegetarian women who had been postmenopausal for more than 1 year. The patients had not used hormone replacement therapy (HRT), soy, or other estrogen-active plant products for at least 16 weeks prior to the study. The group was divided into two equal groups of 15 patients.
The study used nonvegetarian women to avoid potential biasing from higher-than-usual consumption of soy and other legumes, often seen in vegetarian women. Severity of symptoms was self-measured by patients on a scale of zero (no symptoms) to three (severe, interferes with normal activities.)
Thirty women participated in this double-blind, randomized placebo-controlled trial. The women, all of whom had more than five incidents of hot flashes per day, were given a list of isoflavone-rich foods and supplements to avoid.
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Source: HighBeam Research, Promensil reduces frequency and severity of hot flashes.