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High HDL levels explain differences in heart disease risk in white and African-American women.

Women's Health Weekly

| September 12, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 SEP 12 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - The prevalence of coronary heart disease (CHD) risk factors was similar in obese and lean African-American women but was significantly greater in obese white women than in lean white women, according to researchers in the U.S.

"Obesity has been associated with many co-occurring coronary heart disease (CHD) risk factors as well as CHD mortality," said Tracy L. Nelson and colleagues at the University of North Carolina, Colorado State University, and the Centers for Disease Control. "These associations have been shown to vary between African-American and white sample populations."

Data were obtained on 1284 white women and 754 African-American women enrolled in the North Carolina WISEWOMAN (Well-Integrated Screening and Evaluation for Women Across the Nation) study (Obesity and associated coronary heart disease risk factors in a population of low-income African-American and white women: The North Carolina WISEWOMAN Project. Preventive Medicine, 2002;35(1):1-6).

The investigators analyzed associations between obesity and the presence of CHD risk factors (diabetes, hypertension, hypercholesterolemia, low HDL-C) in white and African-American women. Overweight was defined as a body mass index (BMI) 25.0 to 29.99 kg/m[superscript]2, and obese as a BMI greater than or equal to30 kg.m[superscript]2.

Obesity occurred in 35% of the white women, and 34% were overweight. Among African-American women, 59% were obese and 28% were overweight,

The prevalence of three or more co-occurring CHD risk ...

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