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2002 SEP 11 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - The circulation patterns of dengue virus isolates and resultant outbreaks of dengue fever in Kamphaeng Phet, Thailand, have been reported in the American Journal of Epidemiology.
"Dengue virus occurs as four distinct serotypes, each of which causes epidemics throughout the tropical and subtropical regions of the world," explained Timothy P. Endy at the Armed Forces Research Institute of Medical Sciences in Bangkok and his colleagues. "Few studies have examined co-circulation of multiple dengue virus serotypes in a well-defined cohort population over time and their capacity to produce severe dengue disease."
Endy and his collaborators studied dengue virus prevalence and transmission patterns in school children living in northern Thailand in 1998-2000. The investigators identified 108 dengue virus isolates from a total of 167 acute dengue virus infections. DEN-3 (41%) was the major serotype represented, followed by DEN-2 (35%), DEN-1 (23%), and DEN-4 (1%).
All of the isolates were capable of causing severe dengue fever, but the most severe symptoms were induced by DEN-3. Accurate predictions about the serotype most likely to affect a certain area, school, or child could not be made based on predominant serotype-specific ...
Source: HighBeam Research, Report details dengue virus transmission patterns.(Brief Article)