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Gender response to HIV therapy is similar, but women experience more side effects.(Brief Article)

Women's Health Weekly

| August 08, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 AUG 8 - (NewsRx.com & NewsRx.net) -- In a study of men and women treated for HIV at an inner city U.S. clinic, investigators from the Emory University Center for AIDS Research (CFAR) found that although gender did not affect the response to highly active antiretroviral therapy (HAART), women suffered significantly more side effects. Results of the study were presented July 10, 2002, at the 14th International AIDS Conference in Barcelona.

The retrospective study included 222 patients (74 women, 148 men) with HIV treated between May 1996 and October 2001 and followed for at least 2 years. Women in the study were selected randomly from clinic records and matched with men (1:2) by age, race, baseline CD4 count and hepatitis C (HCV) status. Eighty-four percent of patients were African American and 27% had advanced AIDS (defined as a CD4 count

Patients were determined to have successfully responded to HAART therapy if their HIV viral load was undetectable at 24 months. After 2 years of HAART, 34/74 (45.9%) women and 72/148 (48.6%) men had an undetectable viral load. However, women in the ...

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