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2002 AUG 1 - (NewsRx.com & NewsRx.net) -- Women who took oral contraceptives at some point in their lives are no more likely to develop breast cancer between the ages of 35 and 64 than are other women the same age, according to findings from the National Institute of Child Health and Human Development (NICHD) Women's Contraceptive and Reproductive Experiences Study (Women's CARE).
The study appears in the June 27, 2002, issue of the New England Journal of Medicine. The analysis was conducted by Polly A. Marchbanks of the U.S. Centers for Disease Control and Prevention (CDC) and colleagues at NICHD and other research institutions around the country in order to determine whether current or former contraceptive use during the reproductive years increases breast cancer risk. The women studied are members of the first generation of American women to use oral contraceptives.
"Women between the ages of 35 and 64 are more likely to develop breast cancer than are younger women," said Duane Alexander, MD, Director of the NICHD. "It is very reassuring that the NICHD Women's CARE study found no increase in breast cancer risk among past or present oral contraceptive users in this age group."
The researchers interviewed more than 9200 white and black women between the ages of 35 and 64 living in Atlanta, Detroit, Philadelphia, Los Angeles and Seattle. Roughly half of the study participants had recently been diagnosed with breast cancer, while the other half did not have a diagnosis of breast cancer. The women were interviewed in person and asked a series of questions about their use of oral contraceptives and other hormones as well as their reproductive, health and family issues.
"This has been a concern for women who use oral contraceptives," said CDC Acting Director David Fleming, MD. "Previous studies have shown that for healthy women who do not smoke, the health benefits of oral contraceptives far exceed the health risks. This study should ease women's fears about oral contraceptives and breast cancer risk."
Compared with women who had never used oral contraceptives, women who had used any type of oral contraceptive did not have a greater risk of developing breast cancer. Furthermore, examination of multiple aspects of oral contraceptive exposure (ever, current, or former ...