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2002 JUL 24 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Epidemiological data collected in Khartoum, Sudan, has shed light on measles vaccinations coverage and clinical outcomes of measles cases.
S.A. Ibrahim and collaborators working in Sudan collected epidemiological and clinical information on 187 patients with a measles diagnosis. When the investigators ran laboratory tests to establish the measles diagnosis, they confirmed measles in only 141 (75%) patients. The other 46 (25%) patients were ill from other diseases or for other reasons. Surprising, 59% of the patients with a confirmed measles diagnosis had been vaccinated against the disease.
Of the 141 subjects with confirmed measles, 11 (8%) were infected with another virus (varicella zoster and dengue fever most common). Among the 47 patients without measles, another viral infection (usually spotted fever or rubella) was found in 17 (36%) (Measles in suburban Khartoum: An epidemiological and clinical study, Tropical Medicine and International Health, 2002;7(5):442-449).
Differences were apparent between patients with measles and the patients without the disease. Subjects with measles were significantly more likely to have severe cases (p0.0001) and be dehydrated (p=0.01) than were subjects without measles. No significant difference in death rate existed between the two groups (p=0.2), but measles patients, especially ...