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Pneumococcal surveillance emphasizes need for protective strategies.(Brief Article)

Vaccine Weekly

| July 24, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 JUL 24 - (NewsRx.com & NewsRx.net) -- by Roxanne Nelson, staff medical writer - The overall incidence in pneumococcal disease in Denmark has gone down, report researchers, but there is an increase in antibiotic-resistant strains.

In 1996 the rate of pneumococcal diseases was 27/100,000, and declined to 17/100,000 in 1999. This is a major change, said the research team in Copenhagen.

Helle Bosse Konradsen and colleagues at the Statens Serum Institut presented their surveillance data on invasive pneumococcal disease, covering the time period from 1995 to 1999. They analyzed data on more than 5000 pneumococcal isolates and on rates of occurrence, the geographic distribution of serotypes, and antibiotic sensitivity.

A significant change in the proportion of invasive isolates belonging to types 1 and 12F was observed, noted Konradsen and coauthors.

Vaccines utilized against pneumococcal disease provided adequate protection. The 23-valent polysaccharide vaccine, which is primarily used among persons 60 years of age and older, provided serotype coverage of 92.9%. The 7-, 9-, and 11-valent pneumococcal conjugate vaccine, which is given to young children, provided a serotype coverage rate of 71.7%, 75.2%, and 81.4%, in children younger than 2 years (Invasive pneumococcal infections in Denmark from 1995 to 1999: Epidemiology, ...

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