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Women with ovary disease may also have high risk for heart disease.(Brief Article)
2002 JUL 18 - (NewsRx.com & NewsRx.net) -- Women with polycystic ovaries, a common gynecologic disorder, develop stiff arteries that may increase their risk of heart disease and stroke, according to a report in Circulation: Journal of the American Heart Association (June 17, 2002).
Worldwide, at least 20% of women of reproductive age have polycystic ovaries (PCO), a condition in which the ovaries enlarge and develop many small cysts. About three-quarters of these women have polycystic ovary syndrome (PCOS), which is marked by one or more symptoms that include abnormal menstruation, excessive body hair, obesity, and infertility.
In the first study of its kind, researchers compared the elasticity of arteries in women with normal ovaries, those with PCO, and those with PCOS. On average, women with PCOS had arteries nearly twice as stiff as the arteries in women with normal ovaries. Artery stiffness in women with PCO lay roughly midway between the other two groups.
Stiff arteries are an indication of atherosclerosis. As fatty plaque forms and builds in artery walls, the vessels lose some of their elasticity.
"The implication is that a common condition thought to be primarily a gynecological problem may predispose women to heart disease," said lead author Paul Hardiman, MD, a senior lecturer in obstetrics and gynecology at Royal Free and University College Medical School in London.
Hardiman and his colleagues used a sophisticated ultrasound system to examine two arteries in the neck, the common carotid artery and the internal carotid artery, which supply blood to the head. They measured arterial stiffness and compliance (the arteries' ability to dilate when the heart needs to pump more blood through the body). If these arteries are stiff it may indicate more extensive artery disease in the rest of the body.
The 60-patient study involved women from the London area and consisted of three groups of 20 women. One group had a confirmed diagnosis of PCOS. Another group had confirmed PCO but without symptoms of PCOS. Women in the third group were healthy and had normal ovaries.
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Source: HighBeam Research, Women with ovary disease may also have high risk for heart...