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Schering-Plough reports on Peg-Intron and Rebetol combination therapy for hepatitis C.
2002 JUL 9 - (NewsRx.com & NewsRx.net) -- Schering-Plough Corp. (SGP) reported results of several clinical studies presented at the 2002 Digestive Disease Week conference involving Peg-Intron (peginterferon alfa-2b) Powder for Injection in combination with Rebetol (ribavirin, USP) Capsules for the treatment of chronic hepatitis C.
In all, 33 studies with Peg-Intron were presented by clinical investigators.
Peg-Intron and Rebetol combination therapy received U.S. Food and Drug Administration (FDA) approval in August 2001 for the treatment of chronic hepatitis C in patients with compensated liver disease who have not been previously treated with interferon alpha and are at least 18 years of age.
In an oral presentation, investigators reported clinical data from one of the largest clinical trials studying African Americans with hepatitis C. The study indicated that the commonly lower response rate to treatment among African Americans is not related to genotype, as previously believed. Researchers have attributed lower treatment response rates in African Americans to the fact that this patient population predominantly contracts genotype 1 virus, which is the most difficult to treat. In this study, which compared the treatment response rate of African Americans to response rates of non-Hispanic whites, 98% of all patients studied had genotype 1. In the African American patient group, 28% had a virologic response ...
- Hepatitis C Resists Treatment in African Americans.
- Magazine article from: Family Practice News ZOLER, MITCHEL L. February 15, 2000 700+ words
...whites and 3% in African Americans in the second...and 13% in African Americans in the third...one study the response rate was 27% in...withheld from African Americans despite their poor response rate. Instead...
- African Americans respond poorly to hepatitis C treatment.
- Newspaper article from: Hepatitis Weekly June 21, 2004 700+ words
...net) -- African Americans have a significantly lower response rate to treatment...for the low response rate to treatment in African Americans. "This...the lower response rate to treatment among African Americans. Statistical...
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- News wire article from: Ascribe Higher Education News Service May 26, 2004 700+ words
...Newswire) -- African-Americans have a significantly lower response rate to treatment...for the low response rate to treatment in African-Americans. "This...the lower response rate to treatment among African-Americans. Statistical...
- African Americans respond poorly to hepatitis C treatment.(Relevant Research)
- Magazine article from: Black Issues in Higher Education July 1, 2004 700+ words
...N.C. African Americans have a significantly lower response rate to treatment...for the low response rate to treatment in African Americans. "This...the lower response rate to treatment among African Americans. Statistical...
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- Magazine article from: Family Practice News Zoler, Mitchel L. October 1, 1999 700+ words
...Among older African Americans, with a...years, the response rate was 20...with a 60% response rate in whites...rates in African Americans were not...double the response rate among African Americans, said Dr...
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- Press release article from: PR Newswire October 27, 2003 700+ words
...response to treatment in African Americans with chronic hepatitis...in non-Hispanic African Americans compared to Caucasians...sustained virological response rate for Caucasian patients...important because African Americans have historically...
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- Magazine article from: OB GYN News Finn, Robert June 15, 2005 700+ words
...District III were surveyed in 2004, and 863 responded, for a response rate of 30%, reported Dr. Pellegrini, who is in private practice...appear to be faring worse than men (70% vs. 59%), and African Americans appear to be faring worse than other ob.gyns. (78...
- Newly Published Study Investigates Pegasys(R) (peginterferon alfa-2a) and...
- Press release article from: PR Newswire May 25, 2004 700+ words
...infected with HCV genotype 1. To date, this is the highest response rate to treatment observed in a black population." In black...of peginterferon alfa-2a (Pegasys) and ribavirin for African Americans infected with genotype 1, the most common variant of hepatitis...
- SuperGen's Decitabine Achieved 100 Percent Response Rate in Limited Clinical...
- Press release article from: PR Newswire November 2, 2000 700+ words
...In the United States, it affects primarily African Americans, more than 50,000 of whom have the disease...Disease Control and Prevention. One in 12 African-Americans carries the sickle cell trait and most sickle...
- AfricanAmericans Respond Poorly to Hepatitis C Treatment.
- News wire article from: Europe Intelligence Wire May 26, 2004 700+ words
...C. -- African-Americans have a significantly lower response rate to treatment...for the low response rate to treatment in African-Americans. "This...the lower response rate to treatment among African-Americans. Statistical...
Source: HighBeam Research, Schering-Plough reports on Peg-Intron and Rebetol combination therapy...