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2002 JUL 4 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Data from the American Cancer Society's Cancer Prevention Study II (CPS-II) show an increasing risk of breast cancer with increasing body fat (determined by body mass index measurements) in postmenopausal women.
"Epidemiologic evidence suggests a positive association between body mass, adult height, and postmenopausal breast cancer," report J. M. Petrelli and associates at the American Cancer Society. "However, most studies have not been large enough to examine the association across a very wide range of body mass or height and postmenopausal breast cancer mortality."
Petrelli and colleagues analyzed data from 424,168 postmenopausal women who participated in CPS-II, started in 1982. All women were cancer-free upon enrollment. Upon follow-up 14 years later, 2852 of the subjects had died of breast cancer (Body mass index, height, and postmenopausal breast cancer mortality in a prospective cohort of U.S. women, Cancer Causes & Control, 2002;13(4):325-332).
After controlling for potential confounding factors, analysis revealed women who had a body mass index of 40 or higher were three times more likely to die from breast cancer than were women with a BMI from 18.5-20.5. (A person with a BMI of 30 or greater is considered obese.) ...
Source: HighBeam Research, Large study shows strong link between body mass and breast...