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Study: Antacids may be more crucial than calcium in building healthy bones.(Brief Article)
2002 JUN 27 - (NewsRx.com & NewsRx.net) -- The calcium in calcium supplements may not be the primary ingredient responsible for prevention of osteoporosis, according to a study reported by Wayne State University (WSU) School of Medicine (Detroit, Michigan) researchers in the Medicine & Science in Sports & Exercise (2002;34(2):295-302), the official journal of the American College of Sports Medicine.
Antacids may be an overlooked factor in protecting bone health.
Wayne State researchers observed that most calcium supplements on the market are composed mainly of antacids - and the calcium benefit may be secondary to the antacid.
"If you think about it, your bone is like a stick of chalk. If you put it in acid, it's going to dissolve. If you neutralize the acid, the bone stays strong. We began to think about the link between dietary acid intake and osteoporosis, or thinning of the bones," said Dr. Warren Lockette, lead author on the study and professor of neurosurgery at the WSU School of Medicine.
While it's clear that calcium supplements make bones stronger, it isn't clear why. Furthermore, it isn't clear whether calcium is the primary preventive force against osteoporosis. Based on this study, WSU doctors now believe acid metabolism is just as important as calcium consumption in maintaining strong bones.
"We think there's no question that calcium supplementation is beneficial in making bone strong. We're just not so sure it's the calcium in the supplements that is really important. We think it may be the ability of those calcium supplements to buffer against acid that's found in the body - in other words, the antacid effect of most of the supplements," Lockette said.
The Wayne State University study, "Ethnic Differences in Titratable Acid Excretion and Bone Mineralization," initially sought to explain why black Americans have such a low incidence of osteoporosis, even though they generally consume and absorb less calcium than whites. On the other hand, older white women of European descent have the highest rate of osteoporosis, even though they are the largest consumers of dietary and supplemental calcium.
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